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Selected Publications

Zurhove K, Nakajima C, Herz J, Bock HH, May P.
Gamma-secretase limits the inflammatory response through the processing of LRP1.
Sci Signal. 2008 Nov 25;1(47):ra15.
(abstract, full text, podcast)

Terrand J, Bruban V, Zhou L, Gong W, El Asmar Z, May P, Zurhove K, Haffner P, Philippe C, Woldt E, Matz RL, Gracia C, Metzger D, Auwerx J, Herz J, Boucher P.
LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling.
J Biol Chem. 2009 Jan 2;284(1):381-8. Epub 2008 Nov 6. (abstract, full text)

May P, Woldt E, Matz RL, Boucher P.
The LDL receptor-related protein (LRP) family: an old family of proteins with new physiological functions.
Ann Med. 2007;39(3):219-28. Review. (abstract)

Bock HH, Herz J, May P.
Conditional animal models for the study of lipid metabolism and lipid disorders.
Handb Exp Pharmacol. 2007;(178):407-39. (abstract)

Hu L, Boesten LS, May P, Herz J, Bovenschen N, Huisman MV, Berbée JF, Havekes LM, van Vlijmen BJ, Tamsma JT.
Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice.
Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2710-5. Epub 2006 Oct 12. (abstract, full text)

May P.
Neue Funktionen von Lipoproteinrezeptoren.
Dtsch Med Wochenschr. 2006 Jun 9;131(23):1328-31. (summary)

May P, Herz J, Bock HH.
Molecular mechanisms of lipoprotein receptor signalling.
Cellular and Molecular Life Sciences (CMLS) 2005 Oct;62(19-20):2325-38. Review.
(abstract)

Takayama Y, May P, Anderson RG, Herz J.
Low density lipoprotein receptor-related protein 1 (LRP1) controls endocytosis and c-CBL-mediated ubiquitination of the platelet-derived growth factor receptor beta (PDGFR beta).
J Biol Chem. 2005 May 6;280(18):18504-10. Epub 2005 Mar 7. (abstract, full text)

May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J.
Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice.
Mol Cell Biol. 2004 Oct;24(20):8872-83. (abstract, full text)

May, P., Herz, J.:
LDL Receptor-Related Proteins in Neurodevelopment.
Traffic 4 (5): 291-301, 2003

May P, Bock HH, Nimpf J, Herz J.
Differential glycosylation regulates processing of lipoprotein receptors by gamma-secretase.
J Biol Chem. 2003 Sep 26;278(39):37386-92. Epub 2003 Jul 18. (abstract, full text)

May P, Bock HH, Herz J.
Integration of endocytosis and signal transduction by lipoprotein receptors.
Sci STKE. 2003 Apr 1;2003(176):PE12. Review. (abstract, full text)

May P, Reddy YK, Herz J.
Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain.
J Biol Chem. 2002 May 24;277(21):18736-43. Epub 2002 Mar 20. (abstract, full text)

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